Cancer Advisor

Quick Answer The supplements with the strongest human research behind them are vitamin D3 (paired with K2 and magnesium) , curcumin , omega-3 fatty acids , and green tea EGCG — each backed by multiple randomized controlled trials or meta-analyses, though results are mixed rather than uniformly positive. Melatonin looked promising in older, smaller trials, but the largest randomized trial to date found no overall survival benefit. No supplement replaces conventional cancer treatment, and a few — high-dose beta-carotene, vitamin E, and high-dose B6/B12 — have been linked to increased cancer risk in specific groups. Antioxidant supplements are generally discouraged during chemotherapy or radiotherapy unless a doctor directs otherwise. This is an educational overview, not personal medical advice — always loop in your oncology team before starting anything new. Disclosure: Some links in this article are affiliate links (including The Wellness Company and Amazon Associates). If ...

Abstract Trametes versicolor (Turkey Tail) and its water-soluble extracts — especially Polysaccharide-K (PSK, also known as Krestin) and Polysaccharide-Peptide (PSP) — have been studied as adjuvant biological response modifiers in oncology for decades, particularly in East Asia. This review synthesizes clinical, mechanistic, and systematic evidence assessing PSK/PSP in cancer care, focusing on survival outcomes, immune modulation, and safety. While not curative or approved in most Western jurisdictions, Turkey Tail derivatives show modest evidence of benefit as adjuncts to conventional therapies across several cancers. 1. Overview of Turkey Tail and Bioactive Constituents Turkey Tail is a saprophytic bracket fungus with a long history in traditional Chinese and Japanese medicine. Modern interest centers on PSK and PSP , high-molecular-weight polysaccharide complexes extracted from the mycelium. PSK has regulatory approval in Japan as an adjunct in cancer treatment, particularly in g...

Updated August 2026 · Evidence-Ranked Edition This article has been reorganised to rank all 30 integrative cancer interventions by the quality and quantity of available evidence — from randomised controlled trial data down to preclinical laboratory findings. Use this as a structured reference, not a treatment guide. Always consult a qualified healthcare professional before initiating any therapy. ⚠️ Medical Disclaimer: This content is for educational purposes only. Nothing in this article should be used as the basis for initiating, modifying, or discontinuing any cancer treatment without guidance from your treating oncologist or physician. The interventions described here are not approved cancer treatments unless explicitly stated. Diverse cancer hallmarks targeted by repurposed non-oncology drugs. Source: Nature 2024 Introduction Most mainstream guides to “alternative cancer treatments”—including the widely cited Mayo Clinic overview—fo...