Cancer Advisor

Quick Answer: This framework merges OneDayMD's I-PREVENT Cancer Protocol with Dr. Paul Marik and Dr. Justus Hope's ROOT Protocol into a single five-layer system. Layer 1 is diet, metabolic health, and lifestyle — the original I-PREVENT foundation. Layers 2–3 are food-derived nutraceuticals (EGCG, curcumin, vitamin D3, omega-3, berberine, sulforaphane, vitamin C, magnesium, zinc, garlic, melatonin, and more), graded from strongest human-trial evidence to broader supporting data. Layer 4 is an optional Aged Garlic Extract upgrade. Layer 5 is Root 9 — the prescription drugs celecoxib, ivermectin, and mebendazole — which both authors scope strictly to people with confirmed hereditary cancer syndromes under specialist supervision, not general use. This is a prevention framework for healthy adults, not a cancer treatment protocol. Medically reviewed and updated by the OneDayMD Editorial Team | Merged framework published July 12, 2026 | Synthesizes and supersedes two ...

Quick Answer: The ROOT Protocol is a tiered, nutraceutical-based cancer-prevention framework developed by Dr. Paul Marik and Dr. Justus Hope. It begins with a three-agent foundation — green tea EGCG, curcumin, and vitamin D3 — and adds omega-3s, berberine, and sulforaphane in higher tiers. The top tier, Root 9, adds the prescription drugs celecoxib, ivermectin, and mebendazole, and is scoped by its own authors to people with hereditary cancer syndromes under specialist supervision, not general use. It is best understood as a supplement escalation ladder layered on top of the diet and lifestyle foundation described in OneDayMD's I-PREVENT Cancer Protocol . Medically reviewed and updated by the OneDayMD Editorial Team | Last updated July 12, 2026 Table of Contents 1. Why Cancer Prevention Needs a Systems-Level Rethink 2. The Metabolic Drivers Screening Doesn't Address 3. The ROOT Protocol: From 3 Agents to 9 4. Root 3 and Root 4: The Foundational Ti...