Cancer Advisor

Key message: Lifestyle interventions do not replace immunotherapy — but they can meaningfully influence who responds, how well, and how long responses last by shaping metabolism, inflammation, and immune fitness. Why Lifestyle Matters in the Era of Immunotherapy Immune checkpoint inhibitors (PD-1, PD-L1, CTLA-4) have transformed cancer care, yet: Only 20–40% of patients achieve durable responses Many experience immune-related adverse events Metabolic and inflammatory status strongly influence outcomes Lifestyle factors act upstream of the immune system, affecting T-cell energetics, cytokine balance, gut microbiota, and systemic inflammation — all critical to immunotherapy success. Metabolic Health: The Primary Modifier of Immune Response Insulin Resistance and Hyperglycemia Poor glycemic control is associated with: Impaired T-cell activation Increased regulatory T-cell dominance Reduced response rates to checkpoint inhibitors Conversely, improved insulin sensitivity supports: CD8+ T-...

Diet and lifestyle matter for risk reduction and treatment resilience , but they are not standalone cancer therapies. Modern evidence points to metabolism, inflammation, and immune function as the real intermediaries between lifestyle and cancer outcomes. Since this article was first published in 2025, cancer research has moved decisively beyond simplistic claims like “food cures cancer” or “lifestyle alone prevents malignancy.” Large cohort studies, metabolic research, and clinical oncology data now paint a more nuanced picture: Diet influences metabolic signaling , not tumors directly Lifestyle changes lower cancer incidence risk , but rarely eliminate it Outcomes improve most when lifestyle is combined with evidence-based therapy This update reflects current consensus while addressing persistent myths. AACR Cancer Progress Report 2023 / 2024 Diet and Cancer: Association vs Causation What Diet Can Do Strong evidence shows that diet affects: Obesity and insulin resistance Chronic...

Ivermectin, a drug primarily used to treat parasitic infections, has gained attention for its potential anti-cancer properties, particularly in alternative treatment protocols. Popularized by figures like Dr. William Makis, these protocols combine ivermectin with supplements and lifestyle changes to target aggressive cancers. This article explores the science, protocols, case reports, risks, and controversies surrounding ivermectin’s use in cancer treatment, providing a balanced guide for readers. What is the Ivermectin Cancer Protocol? Ivermectin cancer protocols, notably those developed by Dr. William Makis, combine ivermectin with supplements like curcumin, vitamin D, and berberine, alongside dietary and lifestyle changes. These protocols are tailored to cancer severity, with higher doses recommended for aggressive cases. The term “turbo cancers,” used by some proponents, refers to rapidly progressing cancers, though it is not a standard medical term and lacks clear scientific defin...