Cancer Advisor | One Day MD

Quick Answer:   The strongest and most consistent evidence supports a few core cancer-prevention strategies: do not use tobacco in any form; limit or avoid alcohol; maintain a healthy weight through a balanced diet and regular physical activity; and follow a plant-forward, high-fiber, Mediterranean-style eating pattern while minimizing ultra-processed foods and excess added sugar. Although maintaining a healthy diet, engaging in regular physical activity, and achieving a healthy weight remain cornerstones of cancer prevention, growing interest has focused on the potential role of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in reducing cancer risk (AACR Cancer Progress Report 2026). This framework merges OneDayMD's I-PREVENT Cancer Protocol with Dr. Paul Marik and Dr. Justus Hope's ROOT Protocol into a single five-layer system. Layer 1 is diet, metabolic health, and lifestyle — the original I-PREVENT foundation. Layers 2–3 are food-derived nutraceuticals (EG...

Abstract Cancer remains a leading cause of mortality worldwide, with incidence rates projected to rise significantly in the coming decades. While advances in treatment have modestly improved survival, prevention through modifiable risk factors remains underemphasized. This review synthesizes current evidence on the role of diet, lifestyle, and dietary supplements in cancer prevention, drawing on systematic reviews, meta-analyses, and major guideline recommendations. The I-PREVENT CANCER protocol is introduced as a practical, evidence-based framework for reducing cancer risk. Introduction Despite trillions spent on cancer research , cancer still kills around 10 million people a year and is a leading cause of death globally. The incidence of common cancers such as breast, lung, and colon cancer is expected to increase by over 75% between 2022 and 2050.  While treatment advances offer incremental improvements in survival, prevention strategies—particularly those related to diet and l...