Cancer Prevention 101: I-Prevent Cancer Protocol (2025 Edition)

By Editorial Team
Cancer prevention is a multifaceted endeavor, encompassing diet, lifestyle, and supplementation. The I-PREVENT CANCER protocol offers evidence-based strategies to mitigate cancer risk.

Source: AACR Cancer Progress Report 2024

Understanding Cancer and Its Causes

Cancer arises from genetic mutations influenced by lifestyle and environmental factors. Diet, physical inactivity, tobacco use, and exposure to carcinogens significantly contribute to cancer development.​

Dietary Approaches for Cancer Prevention

Adopting a plant-based or Mediterranean diet can reduce cancer risk. These diets emphasize fruits, vegetables, whole grains, and healthy fats while limiting processed foods, sugars, and alcohol. Such nutritional choices provide essential antioxidants and nutrients that support cellular health.​

Lifestyle Modifications

Key lifestyle changes include:​

  • Smoking Cessation: Eliminates exposure to numerous carcinogens.​

  • Weight Management: Maintains hormonal balance and reduces inflammation.​

  • Regular Exercise: Enhances immune function and promotes healthy weight.​

  • Radiation Avoidance: Limits exposure to harmful ionizing radiation.​

  • Stress Reduction: Mitigates chronic inflammation linked to cancer progression.​

Top Anti-Cancer Supplements

Incorporating specific supplements may offer additional protection:​

  1. Vitamin D3, K2, and Omega-3: Vitamin D3 supports immune function and may reduce cancer mortality. Omega-3 fatty acids possess anti-inflammatory properties. Vitamin K2 ensures proper calcium utilization, supporting bone and cardiovascular health. ​

  2. Turmeric (Curcumin): Curcumin, the active compound in turmeric, exhibits anti-inflammatory and antioxidant effects, potentially inhibiting cancer cell growth. ​

  3. Vitamin C: An antioxidant that protects cells from oxidative damage and supports immune function.​

  4. Magnesium: Involved in DNA repair and may reduce cancer risk by maintaining genomic stability.​

  5. Molecular Hydrogen: Acts as an antioxidant, neutralizing harmful free radicals and reducing oxidative stress.​

  6. Zinc: Supports immune function and has antioxidant properties, contributing to DNA repair.​

  7. Probiotics: Maintain gut health, which is crucial for immune function and may influence cancer risk.​

  8. Garlic: Contains organosulfur compounds with potential anti-cancer properties, inhibiting tumor growth. ​

Additional Recommendations

Ensuring quality sleep, regular medical check-ups, and minimizing exposure to environmental toxins further support cancer prevention efforts.​

Conclusion

The most effective way to reduce cancer risk is through a personalized, multi-faceted strategy that emphasizes overall health. This begins with a nutrient-dense, whole-food diet rich in fruits, vegetables, and fiber—while eliminating ultra-processed foods, added sugars, and harmful additives. Combined with a consistent, healthy lifestyle, these foundational habits form a powerful line of defense against cancer.

Each person’s biological makeup, lifestyle, and health status are unique—so prevention strategies should be, too. It’s crucial to empower yourself with accurate, science-backed medical knowledge, especially the kind that may not always be fully addressed by conventional oncology.

Cancer prevention should never rely on a single intervention. It demands a multi-modal approach—where dietary choices, physical activity, stress management, sleep quality, and environmental awareness work together to support immune function and cellular health. While these habits are scientifically validated to reduce cancer risk, no one diet or lifestyle change alone can eliminate that risk entirely.

Optimal prevention involves integration. Diet and lifestyle must be part of a broader, individualized strategy—potentially incorporating medical screenings, targeted supplementation, or additional therapeutic interventions. Since every body responds differently, a flexible and well-rounded plan offers the best chance for long-term protection.

For deeper insights, consult reliable resources such as the American Cancer Society, which provides research-based guidance on cancer prevention by type. For a broader look at causes, treatments, screening options, and prevention strategies categorized by cancer system, visit this detailed resource hub.

Whether you are navigating a current diagnosis, are in recovery, or simply taking proactive steps for your health, consult your healthcare provider to create a prevention or treatment plan that is safe, evidence-based, and tailored specifically for you.


This article is an abridged version of the more comprehensive article (with more than 1000 references). To read the full article: I-PREVENT CANCER protocol: An Evidence-Based Guide to Cancer Prevention (2025 Edition).


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The FLCCC has provided a summary protocol of the key natural and alternative interventions (in order of priority) you can take in order to prevent and treat cancer (Chapter 3: ROLE OF REPURPOSED DRUGS AND METABOLIC INTERVENTIONS IN TREATING CANCER):
  1. Quit smoking. 
  2. Reduce or limit the use of alcohol. 
  3. Lose weight: adopt a healthy diet, manage insulin resistance, and follow a time-restricted eating plan. OneDayMD view: If you have cancer and you are under-weight, this is not for you.
  4. Avoid processed food and processed vegetable oils. 
  5. Avoid sugary beverages and pure fruit juices. 
  6. Limit consumption of red meat to no more than 3 portions/week. 
  7. Vitamin D3: 5000 u/day and adjusted according to vitamin D3 level.
  8. Omega 3 fatty acids: 2-4 g/day.
  9. Green tea catechins: 500-1000 mg/day. Green tea extract should be taken during/after a meal, rather than on an empty stomach. 
  10. Melatonin: 0.75–5 mg (extended/slow release) at night.
  11. Metformin: Metformin should be considered in anyone at high risk of cancer, whether their risk extends from diabetes, pre-diabetes, insulin resistance, chronic viral infection, smoking, or genetics. Requires doctor’s evaluation, approval, and prescription. (Suggested dose ranges from 250-2000 mg daily.) OneDayMD view: If you are not at 'high risk', stick to intervention no. 3.
  12. Regular aerobic exercise and resistance training 30 minutes/day (walking, home strength training, etc.). 
  13. Reduce stress (meditation, yoga, mindfulness exercises, etc.). 
  14. Get at least 8 hours of high-quality sleep (ensure adequate sleep hygiene). 
  15. Avoid known carcinogens. 

Disclaimer

Although this is a comprehensive guide, please do not consider this guide as personal medical advice, but as a recommendation for use with professional providers. Consult with your doctor and discuss with her/him.

Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most strategies are not 100% protective against cancer. It's a continuous struggle between the immune system and the cancer cells.

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