Cancer Advisor

Quick Answer The supplements with the strongest human research behind them are vitamin D3 (paired with K2 and magnesium) , curcumin , omega-3 fatty acids , and green tea EGCG — each backed by multiple randomized controlled trials or meta-analyses, though results are mixed rather than uniformly positive. Melatonin looked promising in older, smaller trials, but the largest randomized trial to date found no overall survival benefit. No supplement replaces conventional cancer treatment, and a few — high-dose beta-carotene, vitamin E, and high-dose B6/B12 — have been linked to increased cancer risk in specific groups. Antioxidant supplements are generally discouraged during chemotherapy or radiotherapy unless a doctor directs otherwise. This is an educational overview, not personal medical advice — always loop in your oncology team before starting anything new. Disclosure: Some links in this article are affiliate links (including The Wellness Company and Amazon Associates). If ...

Updated: September 18, 2026 | Focus: Pancreatic ductal adenocarcinoma (PDAC), L-glutamine, chemotherapy, metabolism and the gut microbiome A 2026 pancreatic cancer study is generating understandable interest: adding oral L-glutamine to gemcitabine plus nab-paclitaxel produced encouraging tumor-response and survival signals in a small phase 1 trial. But the headline needs an important qualifier. The study was single-arm and involved only 16 evaluable patients . The reported 22-month median overall survival is therefore an early clinical signal—not proof that L-glutamine itself makes people with pancreatic cancer live longer. Key takeaway: The 2026 GlutaPanc trial is important because it moves L-glutamine supplementation from an intriguing metabolic and preclinical idea into an early human clinical study in advanced pancreatic cancer. It does not yet establish L-glutamine as standard pancreatic cancer therapy, and it does...