Cancer Advisor

Medically Reviewed by: OneDayMD Editorial Team | Last Updated: September 2026 Ivermectin's US legal status has shifted more in the past 18 months than in the previous two decades. This guide covers where things actually stand in September 2026: the federal rules, which states have changed pharmacy-dispensing law, how to get ivermectin through a legitimate channel, and what the clinical evidence does and doesn't support for its approved and off-label uses. Quick Answer Ivermectin is still classified federally as a prescription-only drug for human use. It has not been reclassified as OTC by the FDA. However, five states — Arkansas, Idaho, Louisiana, Tennessee, and Texas — have passed laws letting pharmacists dispense it without a doctor's prescription, and roughly half a dozen more have active bills. Everywhere else, you need a prescription from a doctor, urgent care provider, or telehealth service. Individual pharmacists retain the right to decline to dispense or ...

Research Guide • Cancer Genomics • Precision Oncology • Multi-Omics The Cancer Genome Atlas (TCGA) was one of the most ambitious cancer genomics programs ever undertaken. A joint initiative of the U.S. National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), TCGA systematically characterized the molecular features of thousands of human tumors across 33 cancer types . The project did something that cancer research had rarely been able to do at this scale: it examined cancer simultaneously through multiple biological layers — including DNA alterations, gene expression, epigenetics, copy-number changes, microRNAs, proteins and clinical information. Why TCGA matters: cancer is not simply a collection of diseases defined by where a tumor is located. TCGA demonstrated how tumors can also be understood through their molecular alterations, signaling pathways, immune environments, metabolic characteristics, cell-of-origin patterns and other...

Cancer Advisor  |  Updated September 19, 2026 The tumor microenvironment (TME) is the biological ecosystem surrounding a tumor. It includes immune cells, cancer-associated fibroblasts (CAFs), blood and lymphatic vessels, extracellular matrix, signaling molecules, nutrients, metabolites, oxygen gradients and physical conditions such as tissue stiffness, acidity and abnormal interstitial pressure. Modern oncology increasingly recognizes that cancer is not simply a collection of malignant cells. Tumor cells continuously interact with their surrounding tissue, while the surrounding tissue can influence tumor growth, invasion, metastasis, immune surveillance, drug delivery and treatment response. The National Cancer Institute defines the TME broadly as the normal cells, molecules and blood vessels surrounding and feeding a tumor, and notes that tumors can change their microenvironment while the microenvironment can influ...