2026 ASCO Guidelines on ctDNA Testing: A Patient’s Guide to Liquid Biopsies
Quick Summary (TL;DR) The American Society of Clinical Oncology (ASCO) has released an updated guideline on circulating tumor DNA (ctDNA) testing (often called a liquid biopsy ) for patients with solid tumors and lymphoma. This simple blood test can detect cancer DNA to help guide treatment. The guidelines recommend ctDNA testing when standard tissue biopsies are too risky, when quick decisions are required, or when a targeted drug demands it. However, because liquid biopsies can miss some mutations, a negative blood test should always be confirmed with a traditional tissue biopsy. Cancer care is rapidly shifting away from one-size-fits-all treatments toward highly personalized medicine. At the forefront of this revolution is a revolutionary blood test known as a liquid biopsy . To clear up confusion and set a gold standard for care, a multidisciplinary expert panel—which intentionally included dedicat...